【学习及工作经历】

• 2003—至今，3044am永利集团，3044am永利集团，教授，有机化学博士生导师；
  

• 2001/9—至今，3044am永利集团，3044am永利集团，教授；

• 1997/9—2001/9，3044am永利集团，化学院，副教授；

• 1995/9—1997/9，3044am永利集团，化学与环境学院，讲师；

• 1992/9—1995/8，中国科学院兰州化学物理研究所，有机化学，博士，导师：金道森，童林荟；

• 1989/9—1992/7，3044am永利集团，有机化学，硕士，导师：黄慧琴；

• 1985/9—1989/7，山东师范大学，化学，学士；

【主讲课程】

• 有机化学

• 生物有机化学

• 有机合成化学

• 综合化学实验

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【研究领域和兴趣】

• 超分子化学

• 功能材料

• 有机合成

• 应用化学

• 环糊精化学

• 精细化学品化学

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【主要论著】

• 通讯作者论文

• 2018年

• 1. Tianxiang Luan, Mingfang Ma, Pengyao Xing, Yajie Wang, Minmin Yang, Yimeng Zhang, Wei An, Qiuhong Cheng and Aiyou Hao*, A Controllable Etching Supramolecular Hydrogel Based on Metal Ion, Soft Matter, 2018, 10, 1753--1758. 
  

• 2017年
  

• 1. Mingfang Ma, Tianxiang Luan, Minmin Yang, Bing Liu, Yajie Wang, Wei An, Bo Wang, Ruipeng Tang and Aiyou Hao*, Self-assemblies of cyclodextrin derivatives modified by ferrocene with multiple stimulus responsiveness†, Soft Matter, 2017, 13, 1534--1538. 

• 2. Li Kong, Feng Zhang, Pengyao Xing, Xiaoxiao Chu, Aiyou Hao*, A binary solvent gel as drug delivery carrier, Colloids and Surfaces A: Physicochem. Eng. Aspects 522 (2017) 577–584. 
  

• 2016年
  

• 1. Yajie Wang,† Pengyao Xing,† Shangyang Li,‡ Mingfang Ma,† Minmin Yang,† Yimeng Zhang,† Bo Wang,† and Aiyou Hao*,†, Facile Stimuli-Responsive Transformation of Vesicle to Nanofiber to Supramolecular Gel via ω-Amino Acid-Based Dynamic Covalent Chemistry, Langmuir 2016, 32, 10705−10711. 

• 2. Xing Pengyao, Chen Hongzhong, Bai Linyi, Hao Aiyou*, Zhao Yanli*, Superstructure Formation and Topological Evolution Achieved by Self-Organization of a Highly Adaptive Dynamer, ACS Nano, 2016, 10(2): 2716-2727.

• 3. Xing Pengyao, Zhao Zhuo, Hao Aiyou*, Zhao Yanli*, Tailoring luminescence color conversion via affinitive co-assembly of glutamates appended with pyrene and naphthalene dicarboximide units, Chem Commun (Camb), 2016, 52(6): 1246-1249.

• 4. Xing Pengyao, Chen Hongzhong, Ma Mingfang, Xu Xingdong, Hao Aiyou*, Zhao Yanli, Light and cucurbit uril complexation dual-responsiveness of a cyanostilbene-based self-assembled system, Nanoscale, 2016, 8(4): 1892-1896.

• 5. Minmin Yang, Pengyao Xing, Mingfang Ma, Yimeng Zhang, Yajie Wang and Aiyou Hao*, Controlled self-organization of cyanostilbene: emission tuning and photo-responsiveness, Soft Matter, 2016, 12, 6038−6042.

• 6. Yimeng Zhang, Shangyang Li, Mingfang Ma, Minmin Yang, Yajie Wang, Aiyou Hao* and Pengyao Xing, Tuning of gel morphology with supramolecular chirality amplification using a solvent strategy based on an Fmoc-amino acid building block, New J. Chem., 2016, 40, 5568−5576.

• 7. Yimeng Zhang, Pengyao Xing, Minmin Yang, Yajie Wang, Bo Wang, Aiyou Hao* and Mingfang Ma, Solvent-polarity-tuned nanostructures assembled from modified octadecylcarbamate with an anthracen moiety, RSC Adv., 2016, 6, 71963−71969.

• 8. Pengyao Xing,ab Zhuo Zhao,c Aiyou Hao*b and Yanli Zhao*ad, Tailoring luminescence color conversion via affinitive co-assembly of glutamates appended with pyrene and naphthalene dicarboximide units, Chem. Commun., 2016, 52, 1246−1249.

• 2015年

• 1. Chu Xiaoxiao, Xing Pengyao, Li Shangyang, Ma Mingfang, Hao Jingcheng, Hao Aiyou*, Dual-tuning multidimensional superstructures based on a T-shaped molecule: vesicle, helix, membraneand nanofiber-constructed gel†, RSC Advances, 2015, (5): 1969-1978.

• 2. Ma Mingfang, Gu Jinge, Yang Minmin, Li Zhaolou, Lu Zhuoqun, Zhang Yimeng, Xing Pengyao, Li Shangyang, Chu Xiaoxiao, Wang Yajie, Li Qi, Lin Minyan, Hao Aiyou*, Controllable self-assemblies of sodium benzoate in different solventenvironments†, RSC Advances, 2015, (5): 70178-70185.

• 3. Zhang Hanqiang, Huang Yihong, Huang Qitong, Wei Chan, Zhang Wuxiang, Yang Weize, Dong Peihui, Hao Aiyou*, Hu Shirong*, Self-assembly of graphitic carbon nitride nanosheets–carbon nanotube compositefor
  electrochemical simultaneous determination of catechol and hydroquinone, Electrochimica Acta, 2015, 176: 28-35.

• 4. Li Shangyang, Zhang Lin, Wang Bo, Ma Mingfang, Xing Pengyao, Chu Xiaoxiao, Zhang Yimeng, Hao Aiyou*, An easy approach for constructing vesicles by using aromatic molecules with beta-cyclodextrin, Soft Matter, 2015, 11(9): 1767-1777.

• 5. Shirong Hu, Wuxiang Zhang, Jianzhong Zheng, Jiangu Shi, Zhongqiu Lin, Ling Zhong，Guixiang Cai, Chan Wei, Hanqiang Zhang, Aiyou Hao*, One step synthesis cadmium sulphide/reduced graphene oxide sandwiched film modified electrode for simultaneous electrochemical determination of hydroquinone, catechol and resorcinol, RSC Advances, 2015，-(5): 18615-18621.

• 6. Ma Mingfang, Shang Wenqing, Xing Pengyao, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, Liu Guangcun, Zhang Yimeng, A supramolecular vesicle of camptothecin for its water dispersion and controllable releasing, Carbohydrate Research, 2015, 402: 208-214.

• 7. Ma Mingfang, Xu Shengguang, Xing Pengyao, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, A multistimuli-responsive supramolecular vesicle constructed by cyclodextrins andtyrosine，Colloid and Polymer Science, 2015, 293: 891-900.

• 8. Zhang Hanqiang, Huang Yihong, Huang Qitong, Wei Chan, Zhang Wuxiang, Kang Lianping, Huang Zhouyi, Hu Shirong*, Hao Aiyou*, Fluorescent probes for “off–on” sensitive and selective detection ofmercury ions and
  L-cysteine based on graphitic carbon nitrid nanosheets†, Journal of Materials Chemistry C, 2015, (3): 2093-2100.

• 2014年

• 1. Hou Yuehui, Li Shangyang, Sun Tao, Yang Jingshu, Xing Pengyao, Liu Wenqi, Hao Aiyou*, Organogels based on beta-cyclodextrin system with molecular recognition property, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2014, 80(3-4): 217-224.

• 2. Xing Pengyao, Chu Xiaoxiao, Ma Mingfang, Li Shangyang, Hao Aiyou*, Melamine as an effective supramolecular modifier and stabilizer in a nanotube-constituted supergel, Chem Asian J, 2014, 9(12): 3440-3450.

• 3. Chu Xiaoxiao, Xing Pengyao, Li Shangyang, Ma Mingfang, Hao Aiyou*, Inorganic salt-tuned multiple self-assemblies of supramolecular beta-cyclodextrin gel, Colloids and Surfaces A: Physicochemical and Engineering
  Aspects, 2014, 461: 11-17.

• 4. Ma Mingfang, Sun Tao, Xing Pengyao, Li Zhaolou, Li Shangyang, Su Jie, Chu Xiaoxiao, Hao Aiyou*, A supramolecular curcumin vesicle and its application in controlling curcumin release，Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 459: 157-165.

• 5. Ma Mingfang, Su Jie, Sheng Xiang, Su Fan, Li Shangyang, Xing Pengyao, Hao Aiyou*, Rapid regio- and enantioselectivities and kinetic resolution of DL-lysine by an effective supramolecular system in water, Journal of Molecular Liquids, 2014, 198: 1-4.

• 6. Xing Pengyao, Chu Xiaoxiao, Du Guangyan, Ma Mingfang, Li Shangyang, Hao Aiyou*, Utilizing dual responsive supramolecular gel to stabilize grapheme oxidein apolar solvents, Colloid and Polymer Science, 2014, 242: 3223-3231.

• 7. 马明放，邢鹏遥，李尚洋，初晓晓，王波，郝爱友*，主客体超分子囊泡及其药物载运性能研究，化学进展，2014，（08）：1317-1328。

• 8. Xing Pengyao, Chu Xiaoxiao, Li Shangyang, Ma Mingfang, Hao Aiyou*, Hybrid Gels Assembled from Fmoc-Amino Acid and Graphene Oxide with Controllable Properties, ChemPhysChem, 2014, 15(11): 2377-2385.

• 9. Li Zhaolou, Hao Aiyou*, Li Xiang, beta-Cyclodextrin supramolecular organogels induced by different carboxylic acids that exhibit diverse morphologies, Journal of Molecular Liquids, 2014, 196: 52-60.

• 10. Ma Mingfang, Guan Yun, Zhang Cai, Hao Jingcheng, Xing Pengyao, Su Jie, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, Stimulus-responsive supramolecular vesicles with effective anticancer activity prepared by cyclodextrin and ftorafur, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 454: 38-45.

• 11. Li Zhaolou, Liu Wenqi, Hao Aiyou*, Gel-sol-gel evolution triggered by formic acid, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 451: 25-32.

• 12. Hu Shirong, Huang Qitong, Lin Yi, Wei Chan, Zhang Hanqiang, Zhang Wuxiang, Guo Zhenbo, Bao Xiuxiu, Shi Jiangu, Hao Aiyou*, Reduced graphene oxide-carbon dots composite as an enhanced material for electrochemical determination of dopamine, Electrochimica Acta, 2014, 130: 805-809.

• 13. Hou Yuehui, Sun Tao, Xin Feifei, Xing Pengyao, Li Shangyang, Hao Aiyou*, Transformation from a heat-set organogel to a room-temperature organogel induced by alcohols, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2014, 79(1-2): 133-140.

• 14. Su Jie, Su Fan, Ma MingFang, Li Shangyang, Xing Pengyao, Hao Aiyou*, Selection of Amino Acids and the Biomimetic Synthesis of Amido Bond in the Presence of beta-CD, Synthetic Communications, 2014, 44(8): 1111-1121.

• 15. Li Shangyang, Xing Pengyao, Zhang Lin, Xin Feifei, Nie Jinhui, Wang Hailu, Ma Mingfang, Wu Yurong, Hao Aiyou*, Controllable self-assembly of an amphiphilic drug with beta-cyclodextrin and alpha-amylase, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 445: 67-74.

• 16. Li Zhaolou, Hao Aiyou*, Hao Jingcheng, Formation of heat-triggered supramolecular organogel in which beta-cyclodextrin as sole gelator, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2014, 441: 8-15.

• 17. Xing Pengyao, Chu Xiaoxiao, Ma Mingfang, Li Shangyang, Zhang Yimeng, Hao Aiyou*, Self- assembly of folic acid/melamine complexes with hierarchy levels: from membranes to porous spherulites and networks, RSC
  Advances, 2014, 4(69): 36633-36639.

• 18. Xing Pengyao, Chu Xiaoxiao, Ma Mingfang, Li Shangyang, Hao Aiyou*, Supramolecular gel from folic acid with multiple responsiveness, rapid self-recovery and orthogonal self-assemblies, Physical Chemistry Chemical
  Physics, 2014, 16(18): 8346-8359.

• 19. Ma Mingfang, Xing Pengyao, Xu Shengguang, Li Shangyang, Chu Xiaoxiao, Hao Aiyou*, Reversible pH-responsive helical nanoribbons formed using camptothecin, RSC Advances, 2014, 4(80): 42372-42375.

• 20. 杨旭，郝爱友*，冯维春，叠氮化钠的水相合成方法及其废液处理，应用化工，2014，（06）：1156-1158+1164。

• 2013年

• 1. Li Shangyang, Xing Pengyao, Hou Yuehui, Yang Jingshu, Yang Xuezhi, Wang Bo, Hao Aiyou*, Formation of a sheet-like hydrogel from vesicles via precipitates based on an ionic liquid-based surfactant and beta-cyclodextrin, Journal of Molecular Liquids, 2013, 188: 74-80.

• 2. Li Shangyang, Sun Tao, Yang Xuezhi, Wang Bo, Xing Pengyao, Hou Yuehui, Su Jie, Hao Aiyou*, Light-responsive drug carrier vesicles assembled by cinnamic acid-based peptide, Colloid and Polymer Science, 2013, 291(11): 2639-2646.

• 3. Li Liuzhong, Wu Yuxiang, Dong Qi, Hao Aiyou*, Cheng Ruihua, Zhong Lei, Liu Boping, Effect of Al-alkyl cocatalyst on ethylene polymerization behavior using silyl chromate (SC)/SiO2 catalyst, Asia-Pacific Journal of Chemical Engineering, 2013, 8(4): 539-546.

• 4. Tao Sun, Mingfang Ma, Hui Yan, Jian Shen, Jie Su, Aiyou Hao*, Vesicular particles directly assembled from the cyclodextrin/UR-144 supramolecular amphiphiles, Colloids and Surfaces A: Physicochemical and Engineering
  Aspects, 2013, 424: 105-112.

• 5. Sun Tao, Yan Hui, Xing Pengyao, Su Jie, Li Shangyang, Hao Aiyou*, Cu(II)-triggered release of paclitaxel from a supramolecular complex，SUPRAMOLECULAR CHEMISTRY, 2013, 25(5): 302-309.

• 6. Pengyao Xing, Tao Sun, Shangyang Li, Aiyou Hao*, Jie Su, Yuehui Hou, An instant-formative heat-set organogel induced by small organic molecules at a high temperature, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2013, 421: 44-50.

• 7. Xing Pengyao, Li Shangyang, Xin Feifei, Hou Yuehui, Hao Aiyou*, Sun Tao, Su Jie, Multi-responsive supramolecular organogel with a crystalline-like structure, Carbohydr Res, 2013, 367: 18-24.

• 8. Xin Feifei, Xing Pengyao, Li Shangyang, Hou Yuehui, Hao Aiyou*, A facile method to construct dual-responsive organogels with color changes, RSC Advances, 2013, 3(44): 21959-21963.

• 9. Xing Pengyao, Chu Xiaoxiao, Li Shangyang, Xin Feifei, Ma Mingfang, Hao Aiyou*, Switchable and orthogonal self-assemblies of anisotropic fibers, New Journal of Chemistry, 2013, 37(12): 3949-3955.

• 10. Xing Pengyao, Chu Xiaoxiao, Li Shangyang, Hou Yuehui, Ma Mingfang, Yang Jingshu, Hao Aiyou*, Self-recovering beta-cyclodextrin gel controlled by good/poor solvent environments, RSC Advances, 2013, 3(44): 22087-22094.

• 11. Xing Pengyao, Sun Tao, Hao Aiyou*, Vesicles from supramolecular amphiphiles, RSC Advances, 2013, 3(47): 24776-24793.

• 12. Xing Pengyao, Chu Xiaoxiao, Du Guangyan, Li Mingzhi, Su Jie, Hao Aiyou*, Hou Yuehui, Li Shangyang, Ma Mingfang, Wu Le, Yu Qiubing, Controllable self-growth of a hydrogel with multiple membranes, RSC ADVANCES, 2013, 3(35): 15237-15244.

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• 第一作者论文

• 1. 郝爱友，黄惠琴，林吉茂，马晨，利用氯化锌/微孔球状硅胶色谱柱制备α-叔丁基醛酮，有机化学，1999，(04)：435-437。

• 2. 郝爱友，亲核重排反应中氢的迁移能力，化学通报(网络版)，1999，-(c00037)：1-3。

• 3. AI-YOU HAO, JI-MAO LIN, LIN-HUI TONG, Selective arylation of β-CD with an ethylenediamino group and characteristics of arylated β-CD dervatives in host-guest complexation, Journal of Inclusion Phenomena and
  Macrocyclic Chemistry, 1999, 34(-): 445-454.

• 4. Ai You Hao, Lin Hui TONG, Min ZHOU, Selective Modification of -CD on the Secondary Side 4: preparation of arylation of β-CD with a Flexible Chain, Chinese Chemical Letters, 1998, 9(1): 13-16.

• 5. Ai You HAO, Lin Hui TONG, Tian Lin YANG, Ji Mao LIN, Characteristic Studies of Arylated -Cyclodextrrins in Host-Guest Complexation with Small Molecules, Chinese Chemical Letters, 1998, 9(3): 265-268.

• 6. 郝爱友，童林荟，环糊精在环境保护中的功能应用，化学试剂，1997，(05)：302-303。

• 7. 郝爱友，童林荟，张复升，光谱活性化环糊精主体与过量客体复合作用性能的简易数学表达式，化学物理学报，1996，(05)：450-452。

• 8. 郝爱友，童林荟，张复升，β－环糊精为TLC流动相添加剂分离对映体，化学通报，1996，(04)：16-18。

• 9. Ai-You HAO, Lin-Hui TONG, Yao-HONG FU, Xia-FEI LAO, Hou-Ming WU, Dimerization constant determination of 6-O-benzoyl-β-CD in aqueous solution, Chinese Chemical Letters, 1996, 7(9): 853-854.

• 10. Ai You Hao, Lin Hui Tong, Fu Sheng Zhang, Xing Ming Gao, Convenient preparation of monoacylated β-cyclodextrin (cyclomaltoheptaose) on the secondary hydroxyl side, Carbohydrate Research, 1995, 277(2): 333-337.

• 11. 郝爱友，童林荟，金道森，环糊精的第二面选择性修饰方法新进展，合成化学，1995，-(03)：208-214。

• 12. 郝爱友，童林荟，金道森，2─氧─(2─羟基丙基)─β─环糊精的简便合成及纯化，化学试剂，1995，(03)：161-162。

• 13. 郝爱友，童林荟，张复升，金道森，亲脂类分子增溶剂单2－氧一(2一羟基丙基)一β一环糊精(单2一HP一β一CD)的制备及其NMR表征，合成化学，1995，(04)：369-371。

• 14. 郝爱友，童林荟，高兴明，张复升，β-萘甲酰化β-环糊精的分子识别性能研究，Acta Physico - Chimica Sinica，1995，(03)：202-205。

• 15. Ai-You Hao, Lin-Hui Tong, Fu-Sheng Zhang, Xing-Ming Gao, and Yoshihisa Inoue, Direct TLC sepration of selected six enantiomersof amino-acids using 2-o-[(R) -2-hydroxypropyl]-β-CD as a mobile phase additive, Analytical Letters, 1995, 28(11): 2041-2048.

• 16. Ai You HAO, Lin Hui TONG, Fu Sheng ZHANG, Dao Sen JIN, A Convenient synthesis of β-cyclodextrion 2- and 3-O-monobenzoate, Chinese Chemical Letters, 1994, 5(8): 645-645.

• 17. 郝爱友，张立新，张海光，化学滴定法测定羟乙基β-环糊精的平均取代度，应用化学，2002，(03)：301-303。

• 18. 郝爱友，王金山，用环糊精合成楔筒状主体分子新模型，Acta Chimica Sinica，2002，60(8)：1536-1538。

• 19. 郝爱友，王金山，辛志荣，水溶性显色型分子识别器--甲基红基乙二胺基羟丙基-β-环糊精，Acta Chimica Sinica，2002，60(8)：1531-1535。

• 20. Ai You HAO, Jin Shan WANG, The Preparation of 2-O-Acetonyl-β-cyclodextrin as One Key Intermediate for Water Soluble β-Cyclodextrin Derivatives, 中国化学快报(英文版), 2002, 13(9): 832-835.

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【科研项目】

• 1. 山东省科学技术厅，低碳烯烃控制聚合与超支液体石蜡生产新技术，2016/1-01-2018/12，主持；
  

• 2. 山东省科学技术厅，高性能聚甘油脂肪酸酯制备新方法，2012/01-2013/12，已结题，主持；

• 3. 山东省科学技术厅，强力医药控缓释新材料：含低聚乳酸基团的环糊精衍生物的制备，2003/01-2004/12，已结题，主持；

• 4. 山东省教育厅，智能提取剂：硅胶载改性环糊精衍生物，2002/01-2003/12，4万元，主持；

• 5. 国家自然科学基金青年基金，29902004，构筑具有楔形筒状空腔的主体分子新模型，2000/01-2002/12，已结题，主持；

• 6. 山东省科学技术厅，合成功能性大环分子构筑高性能药用模型，1999/01-2003/12，已结题，主持；

【科研成果】

•  已发表论文200余篇及十余项专利

• 专著：郝爱友，孙昌俊，曲荣军，徐胜广，刘希光，张文志，精编有机化学教程，3044am永利集团出版社，845000字，2009。

【联合培养情况】

【拟招收研究生情况】

•  每年计划招收2名硕士研究生，1名博士研究生。

•